Search results for "Consolidated Standards of Reporting Trials"

showing 10 items of 11 documents

Calculation of NNTs in RCTs with time-to-event outcomes: A literature review

2008

Abstract Background The number needed to treat (NNT) is a well-known effect measure for reporting the results of clinical trials. In the case of time-to-event outcomes, the calculation of NNTs is more difficult than in the case of binary data. The frequency of using NNTs to report results of randomised controlled trials (RCT) investigating time-to-event outcomes and the adequacy of the applied calculation methods are unknown. Methods We searched in PubMed for RCTs with parallel group design and individual randomisation, published in four frequently cited journals between 2003 and 2005. We evaluated the type of outcome, the frequency of reporting NNTs with corresponding confidence intervals,…

medicine.medical_specialtyEpidemiologyMEDLINEHealth Informaticslaw.inventionRandomized controlled triallawStatisticsConfidence IntervalsHumansMedicineRandomized Controlled Trials as Topiclcsh:R5-920business.industryAbsolute risk reductionConsolidated Standards of Reporting TrialsConfidence intervalClinical trialSample size determinationData Interpretation StatisticalSample SizeNumber needed to treatPhysical therapylcsh:Medicine (General)businessResearch ArticleBMC Medical Research Methodology
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Evaluation of the quality of publications on randomized clinical trials using the Consolidated Standards of Reporting Trials (CONSORT) statement guid…

2011

The main reason for conducting a clinical trial (CT) is to test the effect of a drug or medical procedure to improve treatment of a disease. CTs contribute most when they are rigorously conducted and the results are published adequately. The aim of this study is to assess, using the CONSORT statement guidelines, the quality of reporting of completed CTs conducted at a tertiary hospital to determine which sections of the articles should be improved. CTs published between 2002 and 2008 were identified by searching the MEDLINE and Cochrane Library. Forty of 127 completed CTs were published. There was a marked increase in the number of articles and the quality of the journals that published the…

medicine.medical_specialtyPediatricsMedical procedureAlternative medicineMEDLINEGuidelines as TopicCochrane Librarylaw.inventionHospitals UniversityRandomized controlled triallawmedicineHumansPharmacology (medical)Randomized Controlled Trials as TopicPharmacologybusiness.industryConsolidated Standards of Reporting Trialsnervous system diseasesTest (assessment)Clinical trialSpainFamily medicineJournal Impact FactorPeriodicals as TopicbusinessJournal of clinical pharmacology
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Quality of reporting in abstracts of RCTs published in emergency medicine journals: a protocol for a systematic survey of the literature

2017

Introduction The quality of reporting of abstracts of randomised controlled trials (RCTs) in major general medical journals and in some category-specific journals was shown to be poor before the publication of the ConsolidatedStandards of ReportingTrials (CONSORT) extension for abstracts in 2008, and an improvement in the quality of reporting of abstracts was observed after its publication. The effect of the publication of the CONSORT extension for abstracts on the quality of reporting of RCTs in emergency medicine journals has not been studied. In this paper, we present the protocol of a systematic survey of the literature, aimed at assessing the quality of reporting in abstracts of RCTs p…

Research Reportmedicine.medical_specialtyResearch methodologySystematic surveymedia_common.quotation_subjectAlternative medicineAccident & emergency medicine03 medical and health sciences0302 clinical medicineQuality of reportingProtocolMedicineHumansQuality (business)030212 general & internal medicine1506Abstractmedia_commonRandomized Controlled Trials as TopicProtocol (science)Research ethicsImpact factorbusiness.industryPublicationsConsolidated Standards of Reporting Trials030208 emergency & critical care medicineGeneral Medicinehumanities1691Statistics &research methodsEmergency medicineEmergency MedicineMedline databasebusinessBMJ Open
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Cluster-Randomized Studies.

2018

Background Cluster-randomized trials (CRT) are needed to compare interventions that are allocated to entire groups of subjects, rather than to individuals. Publications about CRT have become steadily more common over the past decade. Readers of such publications should be able to categorize and interpret the findings of CRT correctly while considering the methodological requirements applicable to this type of study. Methods This review is based on a selection of pertinent literature and on the authors' expertise. CRT-specific methodological aspects of the planning, performance, and interpretation of studies are discussed. Results Readers of publications on CRT should check whether due consi…

Research designFuture studiesBiomedical Researchbusiness.industryMEDLINEPsychological interventionConsolidated Standards of Reporting TrialsGuidelines as TopicGeneral MedicineReview Article01 natural sciences010104 statistics & probability03 medical and health sciences0302 clinical medicineCategorizationResearch DesignSelection (linguistics)MedicineCluster AnalysisHumans030212 general & internal medicine0101 mathematicsbusinessCognitive psychologyRandomized Controlled Trials as TopicDeutsches Arzteblatt international
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Cultural adaptation of the Smiling is Fun program for the treatment of depression in the Ecuadorian public health care system: A study protocol for a…

2021

Background Depression is one of the world's major health problems. Due to its high prevalence, it constitutes the first cause of disability among the Americas, where only a very low percentage of the population receives the adequate evidence-based psychological treatment. Internet-Based Interventions (IBIs) are a great alternative to reduce the treatment gap for mental disorders. Although there are several studies in low-and middle-income countries proving IBIs' feasibility and acceptability, there is still little evidence of the effectiveness in diverse social and cultural contexts such as Latin America. Methods Two studies will be described: Study 1 is focused on the cultural adaptation o…

ICD-10 International Classification of Diseases-10GerontologyRCT Randomized Control Trial050103 clinical psychologyOASIS Overall Anxiety Severity and Impairment ScalePsychological interventionAPOI Attitudes Towards Psychological Online Interventionslaw.inventionCultural adaptation0302 clinical medicineCEQ Credibility and Expectancy QuestionnaireRandomized controlled trialODSIS Overall Depression Severity and Impairment Scalelaw030212 general & internal medicineCSQ Client Satisfaction QuestionnaireDepression (differential diagnoses)CRQ Cultural Relevance Questionnaireeducation.field_of_studylcsh:T58.5-58.64Depressionlcsh:Information technology05 social sciencesIBIs Internet-Based InterventionsTiC-P Trimbos/iMTA Questionnaire on Costs on Psychiatric IllnessesSPIRIT Recommendations for Interventional TrialsM.I.N.I. 5.0 MINI International Neuropsychiatric Interview 5.0PC Primary CareQALYs Quality-Adjusted Life-YearsdepressionRandomized Controlled TrialAnxietyRCI Reliable Change Indexmedicine.symptomPsychologyPHQ-9 Patient Health Questionnaire-9WL Waiting Listlcsh:BF1-990PopulationHealth InformaticsContext (language use)cultural adaptationGAD-7 Generalized Anxiety Disorder-703 medical and health sciencesPHC Public Health CareQuality of life (healthcare)EBPTs Evidence-Based Psychological TreatmentsIntervention (counseling)medicine0501 psychology and cognitive sciencesBDI-II Beck Depression Inventory-IIAQoL-6D Assessment of Quality of Life 6 DimensionsMCAR Missing Completely at Randompublic health careeducationPublic Health CareInternet-based interventionFull length ArticleSUS System Usability ScaleLatin Americalcsh:PsychologyWAI-TECH-SF Working Alliance Inventory for Online Intervention-Short Formrandomized controlled trialICERs Incremental Cost-Effectiveness RatiosPANAS Positive and Negative Affect ScheduleE-SF Ecuadorian Cultural Version of Smiling is FunCONSORT Consolidated Standards of Reporting TrialsInternet Interventions
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Quality assessment of randomized controlled trial abstracts on drug therapy of periodontal disease from the abstracts published in dental Science Cit…

2020

Background Randomized controlled trials (RCTs) provide the highest level of evidence and are likely to influence clinical decision-making. This study evaluated the reporting quality of RCT abstracts on drug therapy of periodontal disease and assessed the associated factors. Material and Methods The Pubmed database was searched for periodontal RCTs published in Science Citation Indexed (SCI) dental journals from 2010/01/01 to 2019/07/17. Information was extracted from the abstracts according to a modified Consolidated Standards of Reporting Trials (CONSORT) guideline checklist. The data was analyzed using descriptive statistical analysis and the statistical associations were examined using t…

Research designmedicine.medical_specialtyAbstracting and IndexingMEDLINElaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawInternal medicineHumansMedicinePeriodontologyGeneral DentistryPeriodontal DiseasesRandomized Controlled Trials as TopicIntention-to-treat analysisbusiness.industryResearchConsolidated Standards of Reporting Trials030206 dentistryGuideline:CIENCIAS MÉDICAS [UNESCO]ChecklistConfidence intervalChecklistOtorhinolaryngologyResearch DesignUNESCO::CIENCIAS MÉDICASSurgeryPeriodicals as Topicbusiness
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Randomised double-blind placebo-controlled intervention study on the nutritional efficacy of a food for special medical purposes (FSMP) and a dietary…

2019

ObjectiveTo assess whether the symptoms of veisalgia can be reduced by intense water supply and the intake of antioxidative supplements and plant extracts.MethodsWe performed the world’s largest randomised double-blind placebo-controlled intervention study (214 participants) on the efficacy of a food for special medical purposes (FSMP) against veisalgia symptoms. We analysed the effectiveness of: (1) an FSMP, including distinct plant extracts, vitamins and minerals, and additional (antioxidative) compounds; (2) a dietary supplement only comprising vitamins and minerals and additional (antioxidative) compounds; and (3) a placebo containing only glucose. The study followed the CONSORT (Consol…

0301 basic medicinemedicine.medical_specialtyHealth (social science)NauseaBody waterDietary supplementMedicine (miscellaneous)AlcoholPlaceboDouble blind03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemedicine1506nutritional treatmentlcsh:RC620-627Original ResearchNutrition and Dieteticsbusiness.industryConsolidated Standards of Reporting TrialsIntervention studieslcsh:Nutritional diseases. Deficiency diseases030104 developmental biologychemistrymedicine.symptombusiness030217 neurology & neurosurgeryBMJ Nutrition, Prevention & Health
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MASked-unconTrolled hypERtension management based on office BP or on ambulatory blood pressure measurement (MASTER) Study: a randomised controlled tr…

2018

Introduction Masked uncontrolled hypertension (MUCH) carries an increased risk of cardiovascular (CV) complications and can be identified through combined use of office (O) and ambulatory (A) blood pressure (BP) monitoring (M) in treated patients. However, it is still debated whether the information carried by ABPM should be considered for MUCH management. Aim of the MASked-unconTrolled hypERtension management based on OBP or on ambulatory blood pressure measurement (MASTER) Study is to assess the impact on outcome of MUCH management based on OBPM or ABPM. Methods and analysis MASTER is a 4-year prospective, randomised, open-label, blinded-endpoint investigation. A total of 1240 treated hyp…

HYPERTENSION MANAGEMENTHipertensión.1302masked uncontrolled hypertensionEnfermedades cardiovasculares - Pacientes - Factores de riesgo.office blood pressureMASKED UNCONTROLLED HYPERTENSIONMedicina ClínicaCardiovascular Medicine030204 cardiovascular system & hematologyAMBULATORY BLOOD PRESSURE MONITORINGlaw.invention0302 clinical medicineClinical trialsRandomized controlled triallawBlood Pressure MonitoringMasked Hypertension//purl.org/becyt/ford/3.2 [https]ProtocolMulticenter Studies as Topic1506030212 general & internal medicineCardiovascular system - Diseases - Patients - Risk factors.Blood pressure.OFFICE BLOOD PRESSURERandomized Controlled Trials as TopicSistemas Cardíaco y CardiovascularGeneral MedicineBlood Pressure Monitoring Ambulatory3. Good healthCor MalaltiesEchocardiographyAmbulatoryHypertensionBlood pressure//purl.org/becyt/ford/3 [https]Hipertensióambulatory blood pressure monitoring; hypertension; hypertension management; masked uncontrolled hypertension; office blood pressure; treated hypertensive patientsTREATED HYPERTENSIVE PATIENTS1683medicine.medical_specialtyAmbulatory blood pressureCIENCIAS MÉDICAS Y DE LA SALUDhypertensionHeart Ventriclestreated hypertensive patientPressió sanguínia03 medical and health sciencesAmbulatoryHypertension.medicineAlbuminuriaHumansAntihypertensive AgentsProtocol (science)business.industryConsolidated Standards of Reporting Trialsambulatory blood pressure monitoring; hypertension; hypertension management; masked uncontrolled hypertension; office blood pressure; treated hypertensive patients; Albuminuria; Antihypertensive Agents; Echocardiography; Heart Ventricles; Humans; Masked Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Blood Pressure Monitoring Ambulatorytreated hypertensive patientsambulatory blood pressure monitoringBlood pressurePresión sanguínea.Good clinical practiceEmergency medicinebusinessDeclaration of Helsinkihypertension managementAssaigs clínicsBMJ Open
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Assessing the quality of studies in meta-research: Review/guidelines on the most important quality assessment tools

2020

Systematic reviews and meta-analyses pool data from individual studies to generate a higher level of evidence to be evaluated by guidelines. These reviews ultimately guide clinicians and stakeholders in health-related decisions. However, the informativeness and quality of evidence synthesis inherently depend on the quality of what has been pooled into meta-research projects. Moreover, beyond the quality of included individual studies, only a methodologically correct process, in relation to systematic reviews and meta-analyses themselves, can produce a reliable and valid evidence synthesis. Hence, quality of meta-research projects also affects evidence synthesis reliability. In this overview…

Statistics and ProbabilityCONSORTmedia_common.quotation_subjectPRISMAmeta-researchStrengthening the reporting of observational studies in epidemiology01 natural sciencesAMSTAR-PLUS; AMSTAR2; CONSORT; Cochrane; NOS; PRISMA; STROBE; meta-analysis; meta-research; quality010104 statistics & probability03 medical and health sciences0302 clinical medicineAMSTAR-PLUSBiasSTROBEMedicineHumansPharmacology (medical)Quality (business)AMSTAR2 AMSTAR-PLUS Cochrane CONSORT meta-analysis meta-research NOSPRISMA quality STROBE030212 general & internal medicine0101 mathematicsmedia_commonPharmacologyReview/guidelines on the most important quality assessment tools- PHARMACEUTICAL STATISTICS 2020 [Luchini C. Veronese N. Nottegar A. Shin J. I. Gentile G. Granziol U. SOYSAL P. Alexinschi O. Smith L. Solmi M. -Assessing the quality of studies in meta-research]business.industryConsolidated Standards of Reporting TrialsReproducibility of ResultsEvidence-based medicineNOSJadad scaleAMSTAR2meta-analysisSystematic reviewCochraneRisk analysis (engineering)AMSTAR-PLUS; AMSTAR2; Cochrane; CONSORT; meta-analysis; meta-research; NOS; PRISMA; quality; STROBEqualityResearch DesignMeta-analysisObservational studybusiness
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Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: study protocol for a randomized controlled trial

2021

Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program i…

A ActionDGOJ Directorate General for the Regulation of GamblingCIDI Composite International Diagnostic InterviewPA Positive AffectSPIRIT Standard Protocol Items Recommendations for Interventional TrialsefficacyPsychological interventionMotivational interviewingGE Gambling ExpectanciesDSM-IV Diagnostic and Statistical Manual of Mental Disorders Fourth EditionOASIS The Overall Anxiety Severity and Impairment Scalelaw.inventionDERS Difficulties in Emotion Regulation ScaleRandomized controlled triallawPANAS The Positive and Negative Affect SchedulePsychologyRCT Randomized Controlled TrialUPPS-P The Short UPPS-P Impulsivity ScaleICD-10 International Statistical Classification of Diseases and Related Health Problems 10th RevisionCognitionT58.5-58.64GRCS-S Gambling-Related Cognitions ScalePC Predictive ControlBF1-990EDBs Emotion Driven BehavioursC ContemplationGSEQ Gambling Self-Efficacy QuestionnaireDSM-5 Diagnostic and Statistical Manual of Mental Disorders Fifth EditionAnxietyAddicció a Internetmedicine.symptomMI Motivational InterviewingPsychologyJocs per ordinadorM Maintenancemedicine.medical_specialtyemotion regulationG-SAS The Gambling Symptom Assessment ScaleEMA Ecological Momentary AssessmentODSIS The Overall Depression Severity and Impairment ScaleEfficacyWL Waiting ListIC Illusion of ControlIB Interpretative BiasMFS Monitoring Feedback and SupportCBTHealth InformaticsInformation technologyCBT Cognitive Behavioral TherapyImpulsivityCONSORT-EHEALTH Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online TelehealthISG Perceived Inability to Stop GamblingQuality of life (healthcare)URICA The University of Rhode Island Change Assessment ScaleIntervention (counseling)medicineGD Gambling DisorderSCID-P The Structured Clinical InterviewPsychiatryQLI Quality Life IndexInternetEmotion regulationFull length ArticleSUS System Usability ScalegamblingEMI Ecological Momentary InterventionMINI Mini International Neuropsychiatric InterviewGI Gambling history interview and current gambling situation and related variables assessmentNA Negative AffectGamblingNODS NORC DSM-IV Screen for Gambling ProblemsPFIs Personal Feedback InterventionsDSM-III-R Diagnostic and Statistical Manual of Mental Disorders 3rd Edition RevisedHADS Hospital Anxiety Depression ScaleinternetP Precontemplation
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